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Recent PublicationsThompson, J. and T. Begenisich. 2006. Membrane-delimited Inhibition of Maxi-K Channel Activity by the Intermediate Conductance Ca2+-activated K Channel. J. Gen. Physiol. 127: 159-169. (PDF file) (J. Gen. Physiol. Web Site) Thompson, J. and T. Begenisich. 2005. Two stable, conducting conformations of the selectivity filter in Shaker K+ channels. J. Gen. Physiol. 125: 619-629. (Full Text On-line) Melvin, J. E., D. Yule, T. Shuttleworth, and T. Begenisich. 2005. Regulation of Fluid and Electrolyte Secretion in Salivary Gland Acinar Cells. Ann. Rev. Physiol. 67:445-469. Begenisich, T., T. Nakamoto, C. Ovitt, K. Nehrke, C. Brugnara, S. L. Alper, and J. E. Melvin. 2004. Physiological Roles of the Intermediate Conductance, Ca2+-activated K channel, Kcnn4. J. Biol. Chem. 279:47681-47687. (Full Text On-line) Thompson, J. and T. Begenisich, 2003a. External TEA block of Shaker K channels is coupled to the movement of K ions within the selectivity filter. J. Gen. Physiol. 122:239-246. (Full Text On-line) Thompson, J. and T. Begenisich. 2003b. Functional identification of binding sites at the internal end of the pore in Shaker K+ channels. J. Physiol. 549:107-120. (Full Text On-line) Nehrke, K., C. C. Quinn, and T. Begenisich. 2003. Molecular Identification of the Ca2+-activated K+ channels in parotid acinar cells. Am J. Physiol. Cell Physiol. 284:C535-C546. (Full Text On-line) Arreloa, J., T. Begenisich, K. Nehrke, H-V Nguyen, K. Park, L. Richardson, B. Yang, B.C. Schutte, F.S. Lamb, and J.E. Melvin. 2002. Secretion and cell volume regulation by salivary acinar cells from mice lacking expression of the Clcn3 Cl- channel gene. J. Physiol. 545:207-216. (Full Text On-line) Melvin, J.E., J. Arreola, K. Nehrke, and T. Begenisich. 2002. Ca2+-activated Cl- currents in salivary and lacrimal glands. Current Topics in Membranes. 53:209-230. Arreola, J., T. Begenisich, and J.E. Melvin. 2002. Conformation-dependent regulation of inward rectifier chloride channel gating by extracellular protons. J. Physiol. 541:103-112. (Full Text On-line) Quinn, C.C. and T. Begenisich. 2001. The influence of surface charges on quaternary ammonium block of Shaker K+ channels. J. Mem. Biol. 182:233-243. (Full Text On-line) Park, K., T. Begenisich, and J.E. Melvin. 2001. Protein Kinase A activation phosphorylates the rat ClC-2 Cl- channel but does not change activity. J. Mem. Biol. 182:31-37. (Full Text On-line) Thompson, J and T. Begenisich. 2001. Affinity and Location of an Internal K+ Ion Binding Site in Shaker K Channels. J. Gen. Physiol. 117: 373-384. (Full Text On-line) Nehrke, K., T. Begenisich, J. Pilato, and J.E. Melvin. 2000. C. elegans ClC-type chloride channels: novel variants and functional expression. Am. J. Physiol. 279:C2052-2066. Thompson, J and T. Begenisich. 2000. Electrostatic interaction between charybdotoxin and a tetrameric mutant of Shaker K channels. Biophys. J. 78:2382-2391. Thompson, J. and T. Begenisich. 2000. Interaction between quaternary ammonium ions in the pore of potassium channels: Evidence against an electrostatic mechanism. J. Gen. Physiol. 115:769-782.
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